Homeostasis and inflammation
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چکیده
منابع مشابه
Homeostasis, Inflammation, and Disease Susceptibility
While modernization has dramatically increased lifespan, it has also witnessed the increasing prevalence of diseases such as obesity, hypertension, and type 2 diabetes. Such chronic, acquired diseases result when normal physiologic control goes awry and may thus be viewed as failures of homeostasis. However, while nearly every process in human physiology relies on homeostatic mechanisms for sta...
متن کاملIntestinal Macrophages in Homeostasis and Inflammation
As the intestinal mucosa is continuously exposed to numerous commensal bacteria, it is thought that the gut may possess innate and acquired immune system regulatory mechanisms to prevent excessive inflammatory responses against commensal bacteria. Macrophages are the major population of tissue-resident mononuclear phagocytes, and ISSN 1598-9100 http://dx.doi.org/10.5217/ir.2012.10.4.317 Intest ...
متن کاملMacrophages in intestinal homeostasis and inflammation
The intestine contains the largest pool of macrophages in the body which are essential for maintaining mucosal homeostasis in the face of the microbiota and the constant need for epithelial renewal but are also important components of protective immunity and are involved in the pathology of inflammatory bowel disease (IBD). However, defining the biological roles of intestinal macrophages has be...
متن کاملLymphotoxin-sensitive microenvironments in homeostasis and inflammation
Stromal cell microenvironments within lymphoid tissues are designed to support immune cell homeostasis and to regulate ongoing immune responses to pathogens. Such stromal cell networks have been best characterized within lymphoid tissues including the spleen and peripheral lymph nodes, and systems for classifying stromal cell phenotypes and functions are emerging. In response to inflammation, s...
متن کاملHomeostasis and Inflammation in the Intestine
The gut is home to our largest collection of microbes. The ability of the immune system to coevolve with the microbiota during postnatal life allows the host and microbiota to coexist in a mutually beneficial relationship. Failure to achieve or maintain equilibrium between a host and its microbiota has negative consequences for both intestinal and systemic health. In this Review, we consider th...
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ژورنال
عنوان ژورنال: Ensho
سال: 1982
ISSN: 0389-4290,1884-4006
DOI: 10.2492/jsir1981.2.4_411